The Curbsiders Internal Medicine Podcast

#545: Immune Checkpoint Inhibitor Complications: Recognizing and Managing Immune-Related Adverse Events

Mon, 09 Nov 2026

Recognize immune checkpoint inhibitor (ICI) toxicities. Learn a practical head-to-toe approach to evaluating new symptoms, managing immune-related adverse events (irAEs), and deciding when it’s safe to rechallenge. Dr. Kerry Reynolds, oncologist at Mass General Brigham Cancer Institute and director of the Severe Immunotherapy Complications Service (SIC), joins The Curbsiders to discuss what every internist should know about irAEs.

Claim CME for this episode at https://ce.vcuhealth.org/curbsiders!

Show Segments

Intro

Why internists need to know about ICI toxicities

How checkpoint inhibitors work

Timing of irAEs

Grading the severity of irAEs

Cases:
- Case 1: ICI colitis
- Case 2: ICI hypophysitis
- Case 3: Triple M overlap syndrome: myositis, myocarditis, and myasthenia gravis-like syndrome

Take-home points

Outro

Credits

Written and produced by: Laura Glick MD

Show Notes: Laura Glick MD

Infographic and Cover Art: Zoya Surani

Hosts: Matthew Watto MD, FACP; Nora Taranto MD, MSCE; Laura Glick MD

Reviewer: Sai S Achi MD, MBA, FACP

Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Technical Production: PodPaste

Guest: Kerry Reynolds MD

Disclosures

Bristol Myers Squibb - Clinical trial support funds received by my institution – started 6/2022, ongoing; SAGA Diagnostics Advisory Board - started 12/2022, ended 12/2022; CME Outfitters– Educational Speaker Fees – started 9/2022, ended 1/2023; Medscape – Educational Speaker Fees - started 1/2023, ended 1/2023; Regeneron – Advisory Board – started 6/25/2024, ended 9/30/2024; Up to Date – started 12/1/2024; Gilead – Advisory Board – started 5/2025.

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REBOOT #530 Nutrition with Dr. Joan Salge Blake

Mon, 02 Nov 2026

We have another classic episode for you. Confidently counsel on nutrition, as we discuss different dietary patterns and address common patient queries. We are joined by Dr. Joan Salge Blake (Boston University).

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#544: Updated Pulmonary Embolism Guidelines

Mon, 26 Oct 2026

Review the latest 2026 AHA/ACC multisociety pulmonary embolism guidelines with us, including risk stratification, new clinical categories, acute and extended anticoagulation, advanced therapies, follow-ups, and more. We are joined by Drs. Cyrus Askin and Nick Mark from Critical Care Time!

Claim CME for this episode here: https://ce.vcuhealth.org/curbsiders!

Intro

Initial assessment and diagnostic approach to PE

Evolution of PE classification systems

Acute PE treatment

Advanced therapies

Duration of anticoagulation

Post-discharge follow-up

Chronic thromboembolic disease

Outro

Credits

Producer, writer, show notes, infographic, and cover art: Edison Jyang, MD

Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP

Reviewer: Sai S Achi MD,MBA,FACP

Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Technical Production: PodPaste

Guest: Cyrus Askin, MD; Nick Mark, MD

Disclosures

Dr. Cyrus Askin reports financial disclosures with Astra Zeneca, Speakers Bureau. The Curbsiders report no relevant financial disclosures.

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#543: Navigating Post-Acute Care and Living Options for Older Adults with Dr. Rachel K. Miller

Mon, 19 Oct 2026

Show description:
Learn how to navigate conversations about changing care needs, match older adults with the right site of care, and connect patients and families with resources to make transitions smoother and more successful. We’re joined by Dr. Rachel Miller, to break it all down.

Claim CME for this episode here: https://vcu.cloud-cme.com/course/search?p=4000&curriculum=Podcasts!

Intro

Case

Assessing home environment

Post-hospitalization sites of care

Beyond the hospital: other sites of care

Outro

Credits

Written and Produced by: Ashlee Randolph DO, Rachel K. Miller MD, MSEd, Leah Witt Gaspard, MD

Cover art and infographics by: Ashlee Randolph DO and Rachel K. Miller MD, MSEd

Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP

Reviewer: Rahul Ganatra, MD, MPH

Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Technical Production: PodPaste

Guest: Dr. Rachel K. Miller, MD, MSEd

Disclosures

Dr. Rachel K. Miller reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures.

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#542: Small Intestinal Bacterial Overgrowth (SIBO) with Dr. Purna Kashyap

Mon, 12 Oct 2026

Expertly evaluate and manage small intestinal bacterial overgrowth (SIBO) with Dr. Purna Kashyap (@KashyapPurna, Mayo profile). Identify when and how to test for SIBO and review treatment options.

Claim CME for this episode here: https://vcu.cloud-cme.com/course/search?p=4000&curriculum=Podcasts!

Intro

Case

Topic

Rapid fire questions/Picks of the Week

Outro

Credits

Written, Produced, Infographic and Cover Art by: Elena Gibson MD

Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP

Reviewer: Leah J. Witt Gaspard, MD

Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Technical Production: PodPaste

Guest: Purna Kashyap MBBS

Disclosures

Dr. Kashyap is a member of the scientific advisory board of the International Observatory of Biocodex Microbiota Institute, chair of the scientific advisory board of the American Gastroenterology Association Center for Gut Microbiome Education and Research, ad hoc advisory board member for Pendulum, and Intrinsic Medicine, and advisory board member for 32 Biosciences for which he receives equity option as compensation.The Curbsiders report no relevant financial disclosures.

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Use promo code Curb30 for 30% off all online courses and webcasts. Visit CMEmeeting.org/curbsiders to learn more.

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Sponsor: FIGS

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Sponsor: Quince

Download the Quince app for app-exclusive offers, or go to Quince.com. Get free shipping on your order and 365-day returns. Now available in Canada and the UK, too. And when Quince asks where you heard about them, let them know it was Curbsiders.